Poloxamer

A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)

Also Known As:

Poloxamer 407; Poloxamers; Pluronic F-108; Pluronic F-127; Pluronic F-68; Pluronic F68; Pluronic L-101; Pluronic L-121; Pluronic L-81; Pluronics; Poloxalkol; Poloxamer 188; Poloxamer 213; Poloxamer 2930; Poloxamer 338; 188s, Poloxamer; 213s, Poloxamer; 2930s, Poloxamer; 338s, Poloxamer; 407s, Poloxamer; F68s, Pluronic; Pluronic F 108; Pluronic F 127; Pluronic F 68; Pluronic F108; Pluronic F127; Pluronic F68s; Pluronic L 101; Pluronic L 121; Pluronic L 81; Pluronic L101; Pluronic L121; Pluronic L81; Poloxalkols; Poloxamer 188s; Poloxamer 213s; Poloxamer 2930s; Poloxamer 338s; Poloxamer 407s; Pluronic; alpha- Hydro- omega- hydroxypoly(oxyethylene)a- poly(oxopropylene)b- poly(oxyethylene)a block copolymer

Pharmalogical Action Categories:

Excipients
Surface-Active Agents

Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - Ethylene Glycols: 8
      - Polyethylene Glycols: 3865
        Poloxamer: 1055
Macromolecular Substances: 97
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - Poloxamer: 1055
Biomedical and Dental Materials
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - Poloxamer: 1055
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Polyethylene Glycols: 3865
        Poloxamer: 1055

Laura Challoner Selected Research

Laura Challoner Research Topics

Disease

Drug/Important Bio-Agent (IBA)